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Escherichia coli str. K-12 substr. MG1655 (ecol0)
Gene : carA
DDBJ      :carA         carbamoyl phosphate synthetase small subunit, glutamine amidotransferase
Swiss-Prot:CARA_ECOLI   RecName: Full=Carbamoyl-phosphate synthase small chain;         EC=6.3.5.5;AltName: Full=Carbamoyl-phosphate synthetase glutamine chain;

Homologs  Archaea  59/68 : Bacteria  821/915 : Eukaryota  191/199 : Viruses  0/175   --->[See Alignment]
c.23.16c.8.3
:382 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   2->381 1jdbF PDBj 0.0 99.7 %
:RPS:PDB   2->380 1a9xB PDBj e-117 95.2 %
:RPS:SCOP  2->152 1a9xB1  c.8.3.1 * 6e-77 100.0 %
:RPS:SCOP  153->380 1a9xB2  c.23.16.1 * e-104 98.7 %
:HMM:SCOP  2->152 1a9xB1 c.8.3.1 * 1.1e-56 55.0 %
:HMM:SCOP  153->380 1a9xB2 c.23.16.1 * 2.7e-71 36.8 %
:RPS:PFM   5->133 PF00988 * CPSase_sm_chain 5e-42 61.2 %
:RPS:PFM   196->370 PF00117 * GATase 4e-28 39.7 %
:HMM:PFM   4->133 PF00988 * CPSase_sm_chain 4.8e-59 58.5 130/131  
:HMM:PFM   197->372 PF00117 * GATase 7e-52 36.4 176/192  
:BLT:SWISS 1->382 CARA_ECOLI 0.0 100.0 %

SeqInfo AminoSeq See neighboring genes
Links GIB DAD PEC GenoBase Abbreviations Back to title page
GT:ID AAC73143.1 GT:GENE carA GT:PRODUCT carbamoyl phosphate synthetase small subunit, glutamine amidotransferase GT:DATABASE GIB00009CH01 GT:ORG ecol0 GB:ACCESSION GIB00009CH01 GB:LOCATION 29651..30799 GB:FROM 29651 GB:TO 30799 GB:DIRECTION + GB:GENE carA GB:PRODUCT carbamoyl phosphate synthetase small subunit, glutamine amidotransferase GB:FUNCTION enzyme; Pyrimidine ribonucleotide biosynthesis 1.5.1.3 metabolism; building block biosynthesis; amino acids; arginine 1.5.2.2 metabolism; building block biosynthesis; nucleotide; pyrimidine biosynthesis GB:NOTE GO_process: GO:0006526 - arginine biosynthetic process; GO_process: GO:0006221 - pyrimidine nucleotide biosynthetic process GB:PROTEIN_ID AAC73143.1 GB:DB_XREF GI:1786215 ASAP:ABE-0000118 UniProtKB/Swiss-Prot:P0A6F1 EcoGene:EG10134 GB:GENE:GENE carA LENGTH 382 SQ:AASEQ MIKSALLVLEDGTQFHGRAIGATGSAVGEVVFNTSMTGYQEILTDPSYSRQIVTLTYPHIGNVGTNDADEESSQVHAQGLVIRDLPLIASNFRNTEDLSSYLKRHNIVAIADIDTRKLTRLLREKGAQNGCIIAGDNPDAALALEKARAFPGLNGMDLAKEVTTAEAYSWTQGSWTLTGGLPEAKKEDELPFHVVAYDFGAKRNILRMLVDRGCRLTIVPAQTSAEDVLKMNPDGIFLSNGPGDPAPCDYAITAIQKFLETDIPVFGICLGHQLLALASGAKTVKMKFGHHGGNHPVKDVEKNVVMITAQNHGFAVDEATLPANLRVTHKSLFDGTLQGIHRTDKPAFSFQGHPEASPGPHDAAPLFDHFIELIEQYRKTAK GT:EXON 1|1-382:0| SW:ID CARA_ECOLI SW:DE RecName: Full=Carbamoyl-phosphate synthase small chain; EC=6.3.5.5;AltName: Full=Carbamoyl-phosphate synthetase glutamine chain; SW:GN Name=carA; Synonyms=pyrA; OrderedLocusNames=b0032, JW0030; SW:KW 3D-structure; Amino-acid biosynthesis; Arginine biosynthesis;ATP-binding; Complete proteome; Direct protein sequencing;Glutamine amidotransferase; Ligase; Nucleotide-binding;Pyrimidine biosynthesis. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->382|CARA_ECOLI|0.0|100.0|382/382| GO:SWS:NREP 7 GO:SWS GO:0008652|"GO:cellular amino acid biosynthetic process"|Amino-acid biosynthesis| GO:SWS GO:0006526|"GO:arginine biosynthetic process"|Arginine biosynthesis| GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0006541|"GO:glutamine metabolic process"|Glutamine amidotransferase| GO:SWS GO:0016874|"GO:ligase activity"|Ligase| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| GO:SWS GO:0006221|"GO:pyrimidine nucleotide biosynthetic process"|Pyrimidine biosynthesis| BL:PDB:NREP 1 BL:PDB:REP 2->381|1jdbF|0.0|99.7|380/380| RP:PDB:NREP 1 RP:PDB:REP 2->380|1a9xB|e-117|95.2|378/378| RP:PFM:NREP 2 RP:PFM:REP 5->133|PF00988|5e-42|61.2|129/131|CPSase_sm_chain| RP:PFM:REP 196->370|PF00117|4e-28|39.7|174/185|GATase| HM:PFM:NREP 2 HM:PFM:REP 4->133|PF00988|4.8e-59|58.5|130/131|CPSase_sm_chain| HM:PFM:REP 197->372|PF00117|7e-52|36.4|176/192|GATase| GO:PFM:NREP 3 GO:PFM GO:0004086|"GO:carbamoyl-phosphate synthase activity"|PF00988|IPR002474| GO:PFM GO:0006807|"GO:nitrogen compound metabolic process"|PF00988|IPR002474| GO:PFM GO:0003824|"GO:catalytic activity"|PF00117|IPR000991| RP:SCP:NREP 2 RP:SCP:REP 2->152|1a9xB1|6e-77|100.0|151/151|c.8.3.1| RP:SCP:REP 153->380|1a9xB2|e-104|98.7|228/228|c.23.16.1| HM:SCP:REP 2->152|1a9xB1|1.1e-56|55.0|151/151|c.8.3.1|1/1|Carbamoyl phosphate synthetase, small subunit N-terminal domain| HM:SCP:REP 153->380|1a9xB2|2.7e-71|36.8|228/0|c.23.16.1|1/1|Class I glutamine amidotransferase-like| OP:NHOMO 1908 OP:NHOMOORG 1071 OP:PATTERN 11-1-12222222222-222222121111122231223222222222212232212--1--111--22 2212311111122222223-21112122222222221111222211121222222112111211111232122223332-1222212211112111-1111111111121--------------122222222122222221112222222221222222222221122222222222222223121122122333333333233333333223333332234423333333212222222222222221111131411433223333111222212222221222222111111111111111111111111211221111135-23---111-1-1334422222-3-12222233322111322222-31122211211111221111111111122222222222-22222222223122222222222222222222222222222222222222122221111111111---------------1111211111222222222223222222222222222222222222222222222221222221112222222222222221231311111111112222222221111312122221111111111111111222221111211221222111111111111111111111-222111111122222111111111111-11111111111111111112122222211211111111111112111111121111111111111122222122111122111---1-11----1--122222221122111111223221222222111111111211121111122212112222211111111121332222--------------------------------------2--21222221 11--113-311-1121223222222222222223222322232222232222222222222222222212222321312222222223-22222232223221343-22143322322121222432216H2-3221122212211221222122222226-13211211611412221I1212242542232243232 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 381 STR:RPRED 99.7 SQ:SECSTR #ccEEEEEETTccEEEEEEccccEEEEEEEEEEcccccHHHHHTcGGGcTEEEEEccccccTTcccGGGcccccccccEEEccccccccccTTccccHHHHHHHTTcEEEEcccHHHHHHHHHHHccEEEEEEEcccccHHHHHHHHHHccccTTcccHHHHcccccEEEccccccTTTcccccccGGGccEEEEEEEccccHHHHHHHHHTTEEEEEEETTccHHHHHTTcccEEEEcccccccTTcHHHHHHHHHHHTTccccEEEEHHHHHHHHHTTccEEEEEEEEEEEEEEEEETTTTEEEEEEEEEEEEEccTTccTTEEEEEEETTTccEEEEEEccccEEEEcccTTccccccTTTHHHHHHHHHHHHHHHcEE DISOP:02AL 382-383| PSIPRED ccccEEEEEccccEEEEEEEccccEEEEEEEEEcccccccEEcccHHcccEEEEEcccccccccccHHHHcccccEEEEEEEcccccccccccccccHHHHHHHccccEEEcccHHHHHHHHHHccccEEEEEEcccccHHHHHHHHHccccccccccHHHccccccEEEccccccccccccccccccccccEEEEEEcccHHHHHHHHHHcccEEEEEEccccHHHHHHccccEEEEccccccHHHccHHHHHHHHHHHccccEEEEcHHHHHHHHHcccEEEEccccEEccEEEEEEcccccEEEccccccEEEEccccccccEEEEEEccccEEEEEEEccccEEEEEcccccccccHHHHHHHHHHHHHHHHHHHHcc //